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Lycanthropy, a psychosis in which the patient has delusions of being a wild animal (usually a wolf), has been recorded since antiquity. The Book of Daniel describes King Nebuchadnezzar as suffering from depression that deteriorated over a seven-year period into a frank psychosis at which time he imagined himself a wolf. Among the first medical descriptions were those of Paulus Aegineta during the later days of the Roman Empire. In his description of the symptom complex, Aegineta made reference to Greek mythology in which Zeus turned King Lycaon of Arcadia into a raging wolf. Thereafter, references to lycanthropy appeared in the ancient literature.